Nicotinamide Adenine Dinucleotide
β-NAD+ is a crucial coenzyme found in all living cells, playing a vital role in metabolism by facilitating the transfer of electrons in redox reactions. It is central to energy production, DNA repair, and regulating cellular processes related to aging. β-NAD+ levels naturally decline with age, and supplementation may help restore optimal cellular function and promote longevity.
Specifications：99%
Energy production: β-NAD+ is essential for ATP production, enhancing mitochondrial function and promoting overall energy levels【Yoshino et al., 2018】.
DNA repair: β-NAD+ activates enzymes like PARPs, which help repair DNA damage, supporting cellular health and longevity【Belenky et al., 2007】.
Anti-aging and longevity: β-NAD+ plays a key role in activating sirtuins, enzymes associated with longevity, improving metabolic health and slowing aging processes【Gomes et al., 2013】.
Cognitive function: NAD+ supplementation has been shown to support brain health, improve memory, and enhance cognitive performance【Vaur et al., 2017】.
Mechanisms
β-NAD+ serves as a coenzyme in redox reactions, helping to transfer electrons during cellular respiration and ATP generation in the mitochondria. It also plays a critical role in sirtuin activation, which regulates DNA repair, inflammation, and metabolic pathways linked to aging【Yoshino et al., 2018】. β-NAD+ further supports the activation of PARP enzymes, which assist in maintaining genomic stability and cellular function【Belenky et al., 2007】.
References
Yoshino, J., et al. (2018). NAD+ intermediates: The biology and therapeutic potential of NMN and NR. Cell Metabolism.
Belenky, P., et al. (2007). NAD+ metabolism in health and disease. Cell.
Gomes, A. P., et al. (2013). Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell.
Vaur, P., et al. (2017). NAD+ metabolism as a therapeutic target for age-related degenerative diseases. Journal of Clinical Investigation.