Nicotinamide Adenine Dinucleotide (NAD+) – 99% Pure | China Suppliers and Factory Direct Supply
Energy production
β-NAD+ is essential for ATP production, enhancing mitochondrial function and promoting overall energy levels.
【Yoshino et al., 2018】
DNA repair
β-NAD+ activates enzymes like PARPs, which help repair DNA damage, supporting cellular health and longevity.
【Belenky et al., 2007】
Anti-aging and longevity
β-NAD+ plays a key role in activating sirtuins, enzymes associated with longevity, improving metabolic health and slowing aging processes.
【Gomes et al., 2013】
Cognitive function
β-NAD+ supplementation has been shown to support brain health, improve memory, and enhance cognitive performance.
【Vaur et al., 2017】
Mechanisms
β-NAD+ serves as a coenzyme in redox reactions, helping to transfer electrons during cellular respiration and ATP generation in the mitochondria. It also plays a critical role in sirtuin activation, which regulates DNA repair, inflammation, and metabolic pathways linked to aging【Yoshino et al., 2018】. β-NAD+ further supports the activation of PARP enzymes, which assist in maintaining genomic stability and cellular function【Belenky et al., 2007】.
References
- Yoshino, J., et al. (2018). NAD+ intermediates: The biology and therapeutic potential of NMN and NR. Cell Metabolism.
- Belenky, P., et al. (2007). NAD+ metabolism in health and disease. Cell.
- Gomes, A. P., et al. (2013). Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell.
- Vaur, P., et al. (2017). NAD+ metabolism as a therapeutic target for age-related degenerative diseases. Journal of Clinical Investigation.
Frequently Asked Questions
How does β-NAD+ support energy production in the body?
β-NAD+ serves as an essential coenzyme in redox reactions, facilitating electron transfer during cellular respiration. This process is critical for mitochondrial function and the production of ATP (adenosine triphosphate), which elevates overall cellular energy levels.
What role does β-NAD+ play in DNA repair?
β-NAD+ acts as a key activator for PARP enzymes. These enzymes are vital for detecting and repairing DNA damage, thereby helping to maintain genomic stability, cellular health, and overall longevity.
Can β-NAD+ help with anti-aging and longevity?
Yes, β-NAD+ activates sirtuins, a family of enzymes directly linked to cellular longevity. Sirtuin activation helps regulate metabolic health, reduce inflammation, and slow down various biological aging processes.
How does β-NAD+ supplementation impact cognitive function?
Supplementation with β-NAD+ has been shown to support brain health, enhance memory retention, and boost overall cognitive performance by protecting neural pathways and maintaining cellular function in the brain.
What are the primary biological mechanisms of β-NAD+?
The primary mechanisms include serving as a coenzyme for electron transfer in mitochondria, activating sirtuins to regulate metabolic and anti-aging pathways, and supporting PARP enzymes to ensure stable DNA repair and cellular maintenance.

