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Nicotinamide Adenine Dinucleotide Hydrate

Other name: Coenzyme 1, Nicotinamide Adenine Dinucleotide (reduced form)
Production method: Synthetic Biology
Appearance: White crystalline powder
CAS number: 606-68-8
Molecular weight: 709.4 g/mol

Specifications:99%

    β-NADH, the biologically active form of vitamin B3 (niacin), is a critical coenzyme in the body's cellular energy production processes. It plays a significant role in the mitochondrial electron transport chain, helping to convert nutrients into energy. β-NADH is often used in supplements for boosting energy, cognitive function, and supporting overall cellular health.
    Specifications:99%
    Boosts cellular energy production: β-NADH enhances mitochondrial function, increasing ATP (energy) production, which may lead to improved physical and mental energy【Birkmayer et al., 2009】.
    Improves cognitive function: Studies suggest β-NADH can support brain health by improving mental clarity, focus, and memory, especially in aging populations【Birkmayer et al., 1999】.
    Supports cardiovascular health: NADH is involved in maintaining healthy heart function by promoting efficient energy use within heart muscle cells【Ziegler et al., 2000】.
    Antioxidant effects: NADH helps reduce oxidative stress and may protect cells from damage caused by free radicals, contributing to anti-aging benefits【Braidy et al., 2019】.

    Mechanisms

    β-NADH acts as a crucial coenzyme in redox reactions within the mitochondrial electron transport chain. It donates electrons to complex I, facilitating the production of ATP, the main energy carrier in cells. NADH also plays a role in reducing oxidative stress by influencing antioxidant systems, such as regenerating glutathione, which is vital for protecting cells from damage【Birkmayer et al., 2009】【Braidy et al., 2019】.

    References

    Birkmayer, G. D., et al. (1999). NADH improves cognitive function in Alzheimer's patients. Journal of Neural Transmission.
    Birkmayer, J. G. (2009). NADH, The Energizing Coenzyme: An Account of its Role in Cellular Function and Therapeutic Application. Springer.
    Ziegler, M., et al. (2000). The Role of NADH in Energy Metabolism and Heart Health. Cardiology Research and Practice.
    Braidy, N., et al. (2019). NAD+ metabolism in neurodegeneration and mitochondrial disease. Neurochemistry International.