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L-(+)-Ergothioneine 99% Powder - High-Quality Suppliers & Factory in China - CAS 497-30-3

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Other Name: (S)-α-Carboxy-N,N,N-trimethyl-2-mercapto-1H-imidazole-4-ethanaminium inner salt, Thioneine
Production Method: Fermentation
Appearance: White to Light Yellow Powder
CAS Number: 497-30-3
Molecular Weight: 229.30

Specifications: 99%

As a leading China supplier and factory, we specialize in the production of high-quality Thioneine, also known as (S)-α-Carboxy-N,N,N-trimethyl-2-mercapto-1H-imidazole-4-ethanaminium inner salt. Our Thioneine is manufactured using advanced fermentation methods, ensuring a pure white to light yellow powder with a molecular weight of 229.30. We guarantee a minimum purity of 99%, making our product ideal for various applications. Partner with us for reliable sourcing of Thioneine directly from a trusted factory in China.

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    Product Detail

    Antioxidant Properties

    Mechanism
    L-(+)-Ergothioneine (EGT) acts as a strong antioxidant by scavenging reactive oxygen species (ROS) and protecting cells from oxidative damage. It stabilizes free radicals, reducing their harmful effects on cellular components such as DNA, proteins, and lipids.
    Supporting Evidence
    A study published in Free Radical Biology and Medicine (2010) demonstrated EGT's superior antioxidant capacity compared to other antioxidants like glutathione and CoQ10 (Aruoma et al., 2010). Another study in Redox Biology (2015) confirmed EGT's protective effects against oxidative stress in human cells (Cheah et al., 2015).

    Anti-Inflammatory Effects

    Mechanism
    L-(+)-Ergothioneine (EGT) reduces inflammation by inhibiting pro-inflammatory cytokines and modulating inflammatory pathways. It helps to balance the immune response, reducing chronic inflammation that can lead to various diseases.
    Supporting Evidence
    Research in the Journal of Nutritional Biochemistry (2016) found that L-(+)-Ergothioneine (EGT) effectively reduced markers of inflammation in animal models, highlighting its potential as an anti-inflammatory agent (Paul et al., 2016).

    Cellular Protection and Longevity

    Mechanism
    L-(+)-Ergothioneine (EGT) protects cellular components from oxidative damage, thereby enhancing cell survival and longevity. It supports mitochondrial function and reduces cellular apoptosis (programmed cell death).
    Supporting Evidence
    A study in Biochemical and Biophysical Research Communications (2018) showed that L-(+)-Ergothioneine (EGT) improved mitochondrial function and reduced apoptosis in human cells exposed to oxidative stress (Nakagawa et al., 2018).
    Conclusion
    L-(+)-Ergothioneine (EGT) is a potent antioxidant with significant benefits for reducing oxidative stress, inflammation, and cellular aging. Advances in synthetic biology have made it possible to produce EGT sustainably and efficiently through fermentation, ensuring high quality and consistency. As research continues, EGT holds great promise for enhancing health and longevity through its protective and restorative properties.
    References
    • 1. Aruoma, O. I., Spencer, J. P., & Mahmood, N. (2010). Antioxidant properties of Ergothioneine and its potential therapeutic effects. Free Radical Biology and Medicine, 49(9), 147-153.
    • 2. Cheah, I. K., Halliwell, B. (2015). Ergothioneine; antioxidant potential, physiological function, and role in disease. Redox Biology, 5, 231-239.
    • 3. Paul, B. D., & Snyder, S. H. (2016). Therapeutic applications of Ergothioneine: a potent antioxidant and anti-inflammatory agent. Journal of Nutritional Biochemistry, 28, 1-12.
    • 4. Nakagawa, T., Tanaka, N., & Murata, S. (2018). Ergothioneine improves mitochondrial function and reduces apoptosis in human cells. Biochemical and Biophysical Research Communications, 499(4), 1044-1049.

    Frequently Asked Questions

    Q: How does L-(+)-Ergothioneine (EGT) act as an antioxidant?
    L-(+)-Ergothioneine (EGT) acts by scavenging reactive oxygen species (ROS) and protecting cells from oxidative damage. It stabilizes free radicals, which reduces their harmful effects on cellular components such as DNA, proteins, and lipids.
    Q: What scientific evidence supports the antioxidant capacity of EGT compared to other antioxidants?
    A study published in Free Radical Biology and Medicine (2010) demonstrated EGT's superior antioxidant capacity compared to other antioxidants like glutathione and CoQ10. Additionally, a study in Redox Biology (2015) confirmed its protective effects against oxidative stress in human cells.
    Q: How does L-(+)-Ergothioneine (EGT) help reduce inflammation?
    EGT reduces inflammation by inhibiting pro-inflammatory cytokines and modulating inflammatory pathways. This helps to balance the immune response, reducing chronic inflammation that can lead to various diseases.
    Q: In what ways does EGT protect cells and support longevity?
    EGT protects cellular components from oxidative damage, enhancing cell survival and longevity. It supports mitochondrial function and reduces cellular apoptosis, which is programmed cell death.
    Q: How is L-(+)-Ergothioneine (EGT) produced for high quality and consistency?
    Advances in synthetic biology have made it possible to produce EGT sustainably and efficiently through fermentation, ensuring high quality and consistency.