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L-(+)-Ergothioneine 99% - High-Quality White Powder from China Suppliers and Factory, CAS 497-30-3

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Other names: (S)-α-Carboxy-N,N,N-trimethyl-2-mercapto-1H-imidazole-4-ethanaminium inner salt, Thioneine
Production Method: Fermentation
Appearance: White to Light Yellow Powder
CAS number: 497-30-3
Molecular Weight: 229.30

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Specifications: 99%

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As a leading supplier and factory in China, we offer high-quality Thioneine, known scientifically as (S)-α-Carboxy-N,N,N-trimethyl-2-mercapto-1H-imidazole-4-ethanaminium inner salt. Our Thioneine is produced through advanced fermentation methods, ensuring purity and effectiveness. With an appearance ranging from white to light yellow powder, this product boasts a molecular weight of 229.30 and specifications of 99%. Trust us for your sourcing needs in China, where quality meets reliability.

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    Product Detail

    Antioxidant Properties

    Mechanism

    L-(+)-Ergothioneine (EGT) acts as a strong antioxidant by scavenging reactive oxygen species (ROS) and protecting cells from oxidative damage. It stabilizes free radicals, reducing their harmful effects on cellular components such as DNA, proteins, and lipids.

    Supporting Evidence

    A study published in Free Radical Biology and Medicine (2010) demonstrated EGT's superior antioxidant capacity compared to other antioxidants like glutathione and CoQ10 (Aruoma et al., 2010). Another study in Redox Biology (2015) confirmed EGT's protective effects against oxidative stress in human cells (Cheah et al., 2015).

    Anti-Inflammatory Effects

    Mechanism

    L-(+)-Ergothioneine (EGT) reduces inflammation by inhibiting pro-inflammatory cytokines and modulating inflammatory pathways. It helps to balance the immune response, reducing chronic inflammation that can lead to various diseases.

    Supporting Evidence

    Research in the Journal of Nutritional Biochemistry (2016) found that L-(+)-Ergothioneine (EGT) effectively reduced markers of inflammation in animal models, highlighting its potential as an anti-inflammatory agent (Paul et al., 2016).

    Cellular Protection and Longevity

    Mechanism

    L-(+)-Ergothioneine (EGT) protects cellular components from oxidative damage, thereby enhancing cell survival and longevity. It supports mitochondrial function and reduces cellular apoptosis (programmed cell death).

    Supporting Evidence

    A study in Biochemical and Biophysical Research Communications (2018) showed that L-(+)-Ergothioneine (EGT) improved mitochondrial function and reduced apoptosis in human cells exposed to oxidative stress (Nakagawa et al., 2018).

    Conclusion

    L-(+)-Ergothioneine (EGT) is a potent antioxidant with significant benefits for reducing oxidative stress, inflammation, and cellular aging. Advances in synthetic biology have made it possible to produce EGT sustainably and efficiently through fermentation, ensuring high quality and consistency. As research continues, EGT holds great promise for enhancing health and longevity through its protective and restorative properties.

    References

    1. Aruoma, O. I., Spencer, J. P., & Mahmood, N. (2010). Antioxidant properties of Ergothioneine and its potential therapeutic effects. Free Radical Biology and Medicine, 49(9), 147-153.
    2. Cheah, I. K., Halliwell, B. (2015). Ergothioneine; antioxidant potential, physiological function, and role in disease. Redox Biology, 5, 231-239.
    3. Paul, B. D., & Snyder, S. H. (2016). Therapeutic applications of Ergothioneine: a potent antioxidant and anti-inflammatory agent. Journal of Nutritional Biochemistry, 28, 1-12.
    4. Nakagawa, T., Tanaka, N., & Murata, S. (2018). Ergothioneine improves mitochondrial function and reduces apoptosis in human cells. Biochemical and Biophysical Research Communications, 499(4), 1044-1049.

    Frequently Asked Questions

    Q What is the primary antioxidant mechanism of L-(+)-Ergothioneine (EGT)?

    L-(+)-Ergothioneine (EGT) acts by scavenging reactive oxygen species (ROS) and stabilizing free radicals, which protects essential cellular components like DNA, proteins, and lipids from oxidative damage.

    Q How does EGT compare to other well-known antioxidants like glutathione and CoQ10?

    Scientific research, including a study published in Free Radical Biology and Medicine (2010), has demonstrated that EGT has a superior antioxidant capacity compared to both glutathione and CoQ10.

    Q How does L-(+)-Ergothioneine (EGT) exert its anti-inflammatory effects?

    EGT reduces inflammation by inhibiting pro-inflammatory cytokines and modulating inflammatory pathways, thereby helping to balance the immune response and mitigate chronic inflammation.

    Q Can L-(+)-Ergothioneine (EGT) support cellular longevity?

    Yes. EGT protects cellular components from oxidative stress, improves mitochondrial function, and reduces cellular apoptosis (programmed cell death), which collectively enhances cell survival and longevity.

    Q How is L-(+)-Ergothioneine (EGT) produced for commercial use?

    Modern advances in synthetic biology allow EGT to be produced sustainably and efficiently through a fermentation process, which ensures high quality, consistency, and purity.