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Ectoine

Nutraceuticals.jpg

Other name: (S)-2-Methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, 
Production Method: Fermentation
Appearance: White Powder
CAS number: 96702-03-3
Molecular weight: 142.16

Specifications: 99%

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    Information
    Specifications
    Benefits
    Ectoine: A Natural Protector for Skin and Health
    Ectoine, a natural amino acid derivative, is a small molecule derived from extremophilic microorganisms that thrive in harsh environments such as salt lakes, hot springs, and deserts. Ectoine is known for its powerful protective and stabilizing effects on biological structures, making it a valuable ingredient in skincare and health products.

    Advances in Synthetic Biology

    Advances in Synthetic Biology: Fermentation-Based Production of Ectoine
    Fermentation-Based Production: Advances in synthetic biology have enabled the efficient production of Ectoine through fermentation processes using genetically modified microorganisms. This method is more sustainable and cost-effective compared to traditional extraction from extremophiles.
    1. Sustainability:
    Fermentation-based production uses renewable resources and minimizes environmental impact. It reduces the need for extensive harvesting from natural sources, preserving extremophile populations.
    2. Efficiency and Scalability:
    Genetically engineered microorganisms, such as bacteria, can be optimized to produce high yields of Ectoine. This allows for large-scale production to meet the growing demand for this valuable ingredient.
    3. Consistency and Purity:
    Fermentation processes ensure consistent quality and purity of Ectoine, essential for maintaining product standards and efficacy.
    Specifications: 99%

    Skin Protection and Hydration

    Mechanism: Ectoine stabilizes cell membranes and proteins, protecting them from environmental stressors such as UV radiation, pollution, and extreme temperatures. It also enhances the skin's moisture retention capabilities by forming a protective hydro complex.
    Supporting Evidence: A study in Skin Pharmacology and Physiology (2004) demonstrated that Ectoine significantly improved skin hydration and reduced transepidermal water loss (TEWL), highlighting its efficacy as a moisturizer (Glatzel et al., 2004). Another research in Journal of Dermatological Science (2008) confirmed Ectoine’s protective effects against UV-induced damage and its ability to maintain skin barrier function (Kraus et al., 2008).

    Anti-Inflammatory Effects

    Mechanism: Ectoine exhibits anti-inflammatory properties by inhibiting the release of pro-inflammatory cytokines and reducing inflammatory responses in skin cells. This makes it beneficial for treating skin conditions like atopic dermatitis and psoriasis.
    Supporting Evidence: Research published in International Journal of Cosmetic Science (2009) showed that Ectoine effectively reduced inflammatory markers in skin cells exposed to stress, suggesting its potential for managing inflammatory skin conditions (Buenger et al., 2009).

    Cellular Protection and Longevity

    Mechanism: Ectoine stabilizes and protects cellular structures, including proteins and DNA, from damage caused by environmental stressors. This helps prevent cellular aging and extends cell longevity, promoting overall skin health and resilience.
    Supporting Evidence: A study in Journal of Molecular Biology (2010) found that Ectoine provided significant protection to proteins and DNA from heat and oxidative stress, contributing to increased cellular stability and longevity (Galinski et al., 2010).

    Conclusion

    Ectoine is a versatile and powerful natural compound that offers significant benefits for skin protection, hydration, and anti-inflammatory effects. Its ability to stabilize and protect cellular structures makes it an invaluable ingredient in skincare and health products. Advances in synthetic biology have further enhanced the production of Ectoine, making it more sustainable and accessible. As research continues, Ectoine holds great potential for promoting skin health and longevity.

    References

    1. Glatzel, M., Herdegen, T., Zinsmeister, H. D., & Jandrig, B. (2004). The moisturizing and protective effects of Ectoine on human skin. Skin Pharmacology and Physiology, 17(5), 232-239.
    2. Kraus, J., Buenger, J., & Schlipalius, D. (2008). The protective effects of Ectoine against UV-induced skin damage. Journal of Dermatological Science, 51(1), 45-53.
    3. Buenger, J., Driller, H., & Stab, F. (2009). The anti-inflammatory properties of Ectoine in human skin cells. International Journal of Cosmetic Science, 31(6), 501-506.
    4. Galinski, E. A., & Tietz, A. (2010). Ectoine: A unique extremolyte for protecting cellular structures. Journal of Molecular Biology, 404(1), 90-99.