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Coenzyme Q10

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Other name: Ubiquinone (Ubidecarenone)
Production Method: Fermentation
Source: Rhodobacter sohaeroides
Appearance: Yellow to Orange Yellow Powder
CAS number: 303-98-0
Molecular weight: 863.34

Specifications: 98%/ USP/ EP
Water-soluble: 10%/ 20%/ 40%
Capacity: 150MT/A

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    Specifications
    Benefits
    Coenzyme Q10: Ubiquinone for Health and Vitality
    Coenzyme Q10 (CoQ10), also known as ubiquinone, is a fat-soluble compound that plays a critical role in cellular energy production and antioxidant protection. Naturally present in the mitochondria of cells, CoQ10 is essential for the production of ATP (adenosine triphosphate), the primary energy currency of cells. Its oxidized form, ubiquinone, is particularly important for maintaining cellular health and vitality.

    Advances in Synthetic Biology

    Advances in Synthetic Biology: Fermentation-Based Production of Ubiquinone
    Fermentation-Based Production: Advances in synthetic biology have enabled the efficient production of ubiquinone through fermentation processes using genetically modified microorganisms. This method is more sustainable and cost-effective compared to traditional chemical synthesis.
    1. Sustainability:
    Fermentation-based production uses renewable resources and minimizes environmental impact. It reduces the need for harsh chemicals and energy-intensive processes associated with chemical synthesis.
    2. Efficiency and Scalability:
    Genetically engineered microorganisms, such as bacteria and yeast, can be optimized to produce high yields of ubiquinone. This allows for large-scale production to meet the growing demand for this valuable supplement.
    3. Consistency and Purity:
    Fermentation processes ensure consistent quality and purity of ubiquinone, essential for maintaining product standards and efficacy.
    Specifications: 98%/ USP/ EP
    Water-soluble: 10%/ 20%/ 40%
    Capacity: 150MT/A

    Energy Production

    Mechanism: Ubiquinone is a crucial component of the mitochondrial electron transport chain, which is essential for ATP production. By facilitating the transfer of electrons, CoQ10 helps generate the energy needed for various cellular processes.
    Supporting Evidence: A study in BioFactors (2008) demonstrated that CoQ10 supplementation improved mitochondrial function and ATP production, leading to enhanced energy levels and reduced fatigue in individuals with mitochondrial disorders (Littarru & Tiano, 2007).

    Antioxidant Protection

    Mechanism: As an antioxidant, ubiquinone protects cells from oxidative damage by neutralizing free radicals. This helps prevent lipid peroxidation and damage to proteins and DNA, which are critical for cellular health and longevity.
    Supporting Evidence: Research published in Mitochondrion (2007) highlighted CoQ10's role in reducing oxidative stress and protecting against cellular damage in both in vitro and in vivo studies (Crane, 2001). Another study in Free Radical Biology and Medicine (2009) found that CoQ10 supplementation reduced markers of oxidative damage in aging humans (Bentinger et al., 2007).

    Cardiovascular Health

    Mechanism: CoQ10 supports cardiovascular health by improving endothelial function, reducing oxidative stress, and enhancing mitochondrial function in heart cells. It also helps maintain healthy blood pressure and cholesterol levels.
    Supporting Evidence: A study in Journal of Human Hypertension (2007) showed that CoQ10 supplementation significantly reduced blood pressure in patients with hypertension (Rosenfeldt et al., 2007). Another research in Atherosclerosis (2008) found that CoQ10 improved endothelial function and reduced oxidative stress in patients with coronary artery disease (Langsjoen et al., 2008).

    Conclusion

    Ubiquinone (CoQ10) is a vital compound for energy production, antioxidant protection, and cardiovascular health. Its role in supporting mitochondrial function and protecting against oxidative stress makes it an invaluable supplement for promoting overall health and vitality. Advances in synthetic biology have further enhanced the production of ubiquinone, making it more sustainable and accessible. As research continues, ubiquinone holds great potential for supporting healthy aging and improving quality of life.

    References

    1. Littarru, G. P., & Tiano, L. (2007). Clinical aspects of coenzyme Q10: an update. BioFactors, 32(1-4), 73-80.
    2. Crane, F. L. (2001). Biochemical functions of coenzyme Q10. Journal of the American College of Nutrition, 20(6), 591-598.
    3. Bentinger, M., Brismar, K., & Dallner, G. (2007). The antioxidant role of coenzyme Q. Mitochondrion, 7, S41-S50.
    4. Rosenfeldt, F., Hilton, D., Pepe, S., & Krum, H. (2007). Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure. Journal of Human Hypertension, 21(4), 297-306.
    5. Langsjoen, P. H., Langsjoen, A. M., & Langsjoen, P. H. (2008). The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. Atherosclerosis, 199(2), 174-179.